Recent Compendium Updates
Summary of Changes
Order Code
Test Name
Change Type
Date Effective
Extractable Nuclear Antigen Antibodies (Smith/RNP, Smith, SSA 52, SSA 60, and SSB)
Methodology, Reference Range
September 7, 2021
Fine Needle Aspirate, Cytology
Test Name, Specimen Requirements, CPT Code(s)
September 1, 2021
Test Details
Body Fluid Analysis
NEW TEST
Result Codes:
14725-6 Body Fluid Specimen Type
12254-9 Body Fluid Total Volume
6824-7 Color
9335-1 Clarity
26466-3 WBC, Body Fluid
23860-0 RBC, Body Fluid
26513-2 Neutrophils %
11031-2 Lymphocytes %
30437-8 Monocytes + Macrophages %
26452-3 Eosinophils %
28544-5 Mesothelial Cells %
2344-0 Glucose, Body Fluid
31208-2 Glucose Fluid Source
2881-1 Total Protein, Body Fluid (ARUP)
31208-2.02 Total Protein Fluid Source (ARUP)
634-6 Aerobic Culture
664-3 Gram Stain
635-3 Anaerobic Culture
6825-4 Crystal Analysis, Body Fluid
Performing Laboratory: Cole Diagnostics and ARUP Laboratories
Ordering Recommendation: Crystal analysis is only performed on Synovial fluid. All other tests can be performed on Pericardial, Peritoneal/Ascites, Pleural, or Synovial fluid.
Methodology: Microscopic Examination/ Quantitative Enzymatic/ Quantitative Spectrophotometry
Specimen Requirements:
Preferred Container: Sterile Container AND Lav Top (EDTA) AND Anaerobic Transport Medium
Specimen Preparation: Synovial, pleural, pericardial, peritoneal and any other fluids are obtained by provider. (Only synovial fluid will include a crystal analysis). Portion the fluid between a sterile container, a EDTA lavender tube, AND Anaerobic Transport Medium using the original syringe. Submit to the lab immediately.
Volume Requirements: 6 mL (4 mL)
Stability: Sterile Container for Culture: A: 24 hours; R: Unacceptable; F: Unacceptable; EDTA Lavender Tube: A: 4 hours; R: 24 hours; F: Unacceptable
CPT Code(s): 87070; 89051; 84157; 82945; 89060; 87205; 87075; Reflex to 88108 if pathologist reviews Cell Count/Differential
Body Fluid Cell Count and Differential
NEW TEST
Result Codes:
14725-6 Body Fluid Specimen Type
12254-9 Body Fluid Total Volume
6824-7 Color
9335-1 Clarity
26466-3 WBC, Body Fluid
23860-0 RBC, Body Fluid
26513-2 Neutrophils %
11031-2 Lymphocytes %
30437-8 Monocytes + Macrophages %
26452-3 Eosinophils %
28544-5 Mesothelial Cells %
Performing Laboratory: Cole Diagnostics
Ordering Recommendation: Can be performed on Pericardial, Peritoneal/Ascites, Pleural, or Synovial fluid.
Methodology: Microscopic Examination
Specimen Requirements:
Preferred Container: Lav Top (EDTA)
Specimen Preparation: Synovial, pleural, pericardial, peritoneal and any other sterile body fluids are obtained by provider. Transfer the specimen into an EDTA lavender tube with the syringe used.
Volume Requirements: 2 mL (1 mL)
Stability: A: 4 hours; R: 24 hours; F: Unacceptable
CPT Code(s): 89051; Reflex to 88108 if reviewed by a Pathologist
Extractable Nuclear Antigen Antibodies (Smith/RNP, Smith, SSA 52, SSA 60, and SSB)
Performing Laboratory: ARUP Laboratories
Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay / Semi-Quantitative Multiplex Bead Assay
Reference Interval:
Smith/RNP IgG AB
19 Units or less: Negative
20 to 39 Units: Weak Positive
40 to 80 Units: Moderate Positive
81 Units or greater: Strong Positive
Smith (ENA) Antibody, IgG
29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
SSA-52 (Ro52) (ENA) Antibody, IgG
29 AU/mL or Less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
SS-60 (Ro60) (ENA) Antibody, IgG
29 AU/mL or Less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
SSB (La) (ENA) Antibody, IgG
29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
Fine Needle Aspirate, Cytology
NAME UPDATED - Previously Thyroid FNA Evaluation
Performing Laboratory: ARUP Laboratories
Ordering Recommendation: Establish diagnosis for mass lesions accessible by fine needle aspiration.
Methodology: Microscopy
Specimen Requirements:
Preferred Container: Clean container, Clean container with equal parts cytology fluid, or Slides
Specimen Preparation: Fluid: Transfer FNA fluid into an ARUP Standard Transport tube with equal parts cytology fluid. Unfixed is acceptable if submitted refrigerated within 24 hours of collection; Slides: Transport fixed or unfixed slides.
Stability: Unfixed Fluid: Ambient: 24 hours; Refrigerated: 72 hours; Frozen: Unacceptable; Fixed Fluid: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable; Fixed or Unfixed Slides: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s): 88173; Additional CPT Codes may apply (88172, 88177, 88305, and/or 88342)
Gentamicin, Peak Level, Serum
NAME UPDATED - Previously Gentamicin, Peak Level, Serum or Plasma
Performing Laboratory: ARUP Laboratories
Ordering Recommendation: Optimize drug therapy and monitor patient adherence.
Methodology: Immunoassay
Specimen Requirements:
Preferred Container: Red Top Tube (no gel)
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum from cells within 2 hours of collection and transfer to an ARUP Standard Transport Tube.
Volume Requirements: 1 mL (0.5 mL)
Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s): 80170
Gentamicin, Trough Level, Serum
NAME UPDATED - Previously Gentamicin, Trough Level, Serum or Plasma
Performing Laboratory: ARUP Laboratories
Ordering Recommendation: Optimize drug therapy and monitor patient adherence.
Methodology: Immunoassay
Specimen Requirements:
Preferred Container: Red Top Tube (no gel)
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum from cells within 2 hours of collection and transfer to an ARUP Standard Transport Tube.
Volume Requirements: 1 mL (0.5 mL)
Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s): 80170
RhD Gene (RHD) Copy Number
Performing Laboratory: ARUP Laboratories
Ordering Recommendation: Determine the number of copies of the RHD gene. Does not identify or distinguish between partial and weak RHD genotypes.
Methodology: Polymerase Chain Reaction/Fluorescence Monitoring
Specimen Requirements:
Preferred Container:
Fetal Genotyping: Cultured amniocytes, Two T-25 flasks at 80 percent confluency. If unable to culture aminocytes, submit WITH maternal cell contamination specimen: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Parental genotyping: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Specimen Preparation:
Cultured amniocytes: Transport two T-25 flasks at 80 percent confluency filled with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Maternal cell contamination specimen: Transport whole blood.
Parental genotyping: Transport whole blood.
CPT Code(s): 81403
Unacceptable: Expired specimens. Frozen specimens submitted in glass collection tubes.
Volume Requirements: Whole blood: 3 mL (1 mL)
Stability: Fetal Specimen: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable; Whole blood or maternal cell contamination specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month